How Microtome Work？

Release time:

2025-01-10 10:18

Microtome is an important laboratory equipment which is widely used in pathology, biology, medicine and other fields. Its main function is to cut tissue samples into thin and uniform sections for microscopic observation and research. The working principle of Microtome mainly involves many aspects such as machinery, transmission and control.

I. Basic Structure

Microtome is mainly composed of base, knife frame, slicing disk, transmission system, control system and other parts. Among them, the knife frame is responsible for installing the slicing knife, the slicing disk is the place where the samples come into contact with the knife, the transmission system drives the knife frame to carry out the cutting action, and the control system is responsible for the operation control of the whole equipment.

Working Principle

1. Transmission system: the motor drives the transmission belt to drive the slicing disk to rotate. The transmission system usually adopts precision bearings and gears to ensure stable transmission speed and force.
2. Knife holder and blade: The knife holder is fixed on the upper part of the Microtome, and the blade is mounted on the knife holder. When the transmission system works, the blade makes a cutting movement.
3. sample fixation: the sample to be cut is fixed on the slicing disk, and the position in contact with the blade is the cutting point.
4. control system: the control system is the core part of the Microtome, which can control the start, stop, speed, etc. of the equipment. The operator can input commands through the control panel to realize automatic or semi-automatic operation.
5. Cutting process: When the equipment starts, the motor drives the transmission system to rotate the blade for cutting. The operator can get the required slice thickness by adjusting the position and angle of the slicing disk and the depth of the blade.
6. Auxiliary devices: Some advanced Microtomes are also equipped with auxiliary devices such as automatic liquid refilling and automatic slice trimming to improve working efficiency and slice quality.

Advantageous features

Microtome has the advantages of easy operation, high cutting precision and uniform slice thickness. Compared with the traditional manual slicing method, the Microtome greatly improves the working efficiency and slice quality, and reduces the human error.

Application fields

Microtome is widely used in pathology, biology and other fields of research and teaching work, especially in pathological diagnosis plays an important role. Through the Microtome, doctors can get clear tissue slices, which provide an important basis for the diagnosis and treatment of diseases.

In short, Microtome realizes efficient and precise cutting of tissue samples through its complex mechanical and control system, which provides important support for scientific research and medical work.

Microtome

Microtome Operation Procedure

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Microtome Operation Procedure

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